Simulating Oncology Trials using an Illness-Death Model


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Documentation for package ‘simIDM’ version 0.0.5

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simIDM-package 'simIDM' Package
addStaggeredEntry Staggered Study Entry
assert_intervals Assertion for vector describing intervals
assert_positive_number Assertion for Positive Number
censoringByNumberEvents Event-driven censoring.
exponential_transition Transition Hazards for Exponential Event Times
ExpSurvOS OS Survival Function from Constant Transition Hazards
ExpSurvPFS PFS Survival Function from Constant Transition Hazards
getCensoredData Helper function for 'censoringByNumberEvents'
getClinicalTrials Simulation of a Large Number of Oncology Clinical Trials
getDatasetWideFormat Conversion of a Data Set from One Row per Transition to One Row per Patient
getEventsAll Number of recruited/censored/ongoing Patients.
getNumberEvents Helper Function for 'trackEventsPerTrial'
getOneClinicalTrial Simulation of a Single Oncology Clinical Trial
getOneToTwoRows Transitions from the Intermediate State to the Absorbing State
getPCWDistr Piecewise Exponentially Distributed Event Times
getPCWHazard Piecewise Constant Hazard Values
getSimulatedData Simulate Data Set from an Illness-Death Model
getSumPCW Sum of Two Piecewise Constant Hazards
getTimePoint Time-point by which a specified number of events occurred.
getWaitTimeSum Event Times Distributed as Sum of Weibull
integrateVector Helper for Efficient Integration
PCWInversionMethod Single Piecewise Exponentially Distributed Event Time
piecewise_exponential Transition Hazards for Piecewise Exponential Event Times
pwA Cumulative Hazard for Piecewise Constant Hazards
PwcOSInt Helper Function of 'PWCsurvOS()'
PWCsurvOS OS Survival Function from Piecewise Constant Hazards
PWCsurvPFS PFS Survival Function from Piecewise Constant Hazards
simIDM 'simIDM' Package
trackEventsPerTrial Event tracking in an oncology trial.
WeibOSInteg Helper Function for 'WeibSurvOS()'
WeibSurvOS OS Survival Function from Weibull Transition Hazards
WeibSurvPFS PFS Survival Function from Weibull Transition Hazards
weibull_transition Transition Hazards for Weibull Distributed Event Times