Package: crispRdesignR
Type: Package
Title: Guide Sequence Design for CRISPR/Cas9
Version: 1.1.7
Encoding: UTF-8
Authors@R: c(
    person("Dylan", "Beeber", email = "dylan.beeber@gmail.com", role = c("aut", "cre")),
    person("Frederic", "Chain", role = "aut"))
Description: Designs guide sequences for CRISPR/Cas9 genome editing and 
    provides information on sequence features pertinent to guide 
    efficiency. Sequence features include annotated off-target 
    predictions in a user-selected genome and a predicted efficiency 
    score based on the model described in Doench et al. (2016) 
    <doi:10.1038/nbt.3437>. Users are able to import additional genomes 
    and genome annotation files to use when searching and annotating 
    off-target hits. All guide sequences and off-target data can be 
    generated through the 'R' console with sgRNA_Design() or through 
    'crispRdesignR's' user interface with crispRdesignRUI(). CRISPR 
    (Clustered Regularly Interspaced Short Palindromic Repeats) and the 
    associated protein Cas9 refer to a technique used in genome editing.
URL: <https://github.com/dylanbeeber/crispRdesignR>
License: GPL-3
Depends: R (>= 2.10)
Imports: Biostrings, gbm, GenomicRanges, BiocGenerics, IRanges,
        GenomeInfoDb, S4Vectors, rtracklayer, stringr, vtreat, shiny,
        DT
Suggests: BSgenome.Scerevisiae.UCSC.sacCer3
RoxygenNote: 7.1.0
NeedsCompilation: no
Packaged: 2023-04-11 20:33:17 UTC; admin
Author: Dylan Beeber [aut, cre],
  Frederic Chain [aut]
Maintainer: Dylan Beeber <dylan.beeber@gmail.com>
Repository: CRAN
Date/Publication: 2023-04-12 09:50:02 UTC
Built: R 4.6.0; ; 2026-01-12 04:38:33 UTC; windows
