tsdf

What is it?

tsdf calculates optimal Zhong’s two-/three-stage Phase II designs, generates decision tables for two-/three-stage Phase I dose-finding, and allows users to run dose-finding simulations with custom decision tables. ### Installation To install from CRAN:

install.packages("tsdf")

References

[1] Bob Zhong, Single-arm phase IIA clinical trials with go/no-go decisions, Contemp Clin Trials, 2012

[2] Wenchuan Guo and Bob Zhong, Target toxicity design for phase I dose-finding, Statistical Theory and Related Fields, 2021