RNentropy 1.3.3
RN_iso_calc and RNentropy_iso_switch no
longer return res, which duplicated
gene_status and pv.
- The default gene-level threshold of
RN_iso_select
(gene_pv) is now 0.05 (previously 0.01).
- Corrected the package citation, which now lists the 2018 Nucleic
Acids Research article and the 2021 Methods in Molecular Biology
chapter.
- Corrected and completed several help pages: an overview of both
analyses in the package help, the exact testability rule of
min_expr, cross-references between the isoform-switch
functions, fixes to the dataset descriptions, and removal of outdated
copies of the source code from the examples.
RNentropy 1.3.2
RN_iso_select now combines the sample p-values of each
TESTED gene into a gene-level p-value with the Simes method and compares
it with the threshold, without correction across genes. The threshold
argument lpv_t is renamed gene_pv, the
method argument and the lpv_adj component are
removed, and the gene-level p-values are returned as
gene_pv. selected reports the gene-level
p-value (ISO_GENE_PV) next to the uncorrected per-sample
p-values.
RN_iso_calc and RNentropy_iso_switch
return the per-sample p-values as pv (formerly
lpv), with columns named ISO_PV_<sample>
(formerly ISO_LPV_<sample>).
- Renamed the sample columns of
RN_IsoSwitch_Example_S7
and of the compact S7 example file to plain tissue names
(brain, heart, kidney,
liver, lung, muscle).
RNentropy 1.3.1
- Added
RN_iso_select to apply multiple-testing
correction to isoform-switch local p-values and retain genes significant
in at least one sample.
- Added runnable file-based examples for the standard and
isoform-switch workflows using a shared synthetic regression
dataset.
RNentropy 1.3.0
- Initialized the public GitHub development repository from the
verified CRAN 1.2.3 release.
- Added continuous integration and repository provenance
metadata.
- Added
RN_iso_calc and RNentropy_iso_switch
for the analysis of isoform switching, with explicit testability
information and results validated against the independent C++
implementation.
- Added the complete historical S7 isoform-switch example as the
compressed
RN_IsoSwitch_Example_S7 package dataset.
RNentropy 1.2.3
- Fixed small bug in .RN_design_check preventing compatibility with R
>=4.2.0
- Added reference to new publication
- Removed unneeded initialization of .Random.seed
- Fixed a few typos in the documentation
- Added README.md, NEWS.md, and cran-comments.md files